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產(chǎn)品概述
| 名稱 | GC-2spd(ts) (小鼠精母細(xì)胞) (STR鑒定正確) |
| 別稱 | GC-2 |
| 種屬 | 小鼠 |
| 生長(zhǎng)特性 | 貼壁細(xì)胞 |
| 細(xì)胞形態(tài) | 上皮細(xì)胞樣 |
| 凍存條件 | 凍存液：55% 基礎(chǔ)培養(yǎng)基+40%FBS+5%DMSO 溫度：液氮 |
| 培養(yǎng)方案A（默認(rèn)） |
培養(yǎng)條件:
氣相：空氣，95%；CO2，5%, 溫度：37℃
|
| 推薦傳代比例 | 1:4-1:6 |
| 推薦換液頻率 | 2-3次/周 |
| 背景描述 | The cells have lost their differentiation potential, and are currently arrested at a premeiotic stage. |
| 年齡（性別） | 雄性；6周齡 |
| 組織來源 | 精母細(xì)胞；SV40大T抗原轉(zhuǎn)染 |
| 細(xì)胞類型 | 條件永生化細(xì)胞系 |
| 生物安全等級(jí) | BSL-2 |
| 應(yīng)用領(lǐng)域 | This cell line may be useful for the study of spermatogenesis. |
| 保藏機(jī)構(gòu) | ATCC; CRL-2196 BCRC; 60313 |
STR鑒定
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STR位點(diǎn)信息
18-3 16,17 6-7 17 5-5 14,17,18,19 X-1 28 1-2 13,19 7-1 26.2,29 8-1 16 1-1 17 19-2 13 15-3 22.3 12-1 17 6-4 18 4-2 20.3 3-2 14 2-1 16 13-1 15.2,17.1
11-2 16 17-2 15 -
STR鑒定圖
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參考文獻(xiàn)
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The gut metabolite 3-hydroxyphenylacetic acid rejuvenates spermatogenic dysfunction in aged mice through GPX4-mediated ferroptosis(2023/09/27)
作者：Zirun Jin, Yuzhuo Yang, Yalei Cao
期刊：Microbiome
DOI：10.1186/s40168-023-01659-y
影響因子 ：15.500
引用產(chǎn)品：CL-0593
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Gut-Derived Exosomes Mediate the Microbiota Dysbiosis-Induced Spermatogenesis Impairment by Targeting Meioc in Mice(2024/03/25)
作者：Tong Chen, Boqi Zhang, Guitian He
期刊：Advanced Science
影響因子 ：15.100
引用產(chǎn)品：CL-0593
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The necroptosis-mediated imbalance of mitochondrial dynamics is involved in DEHP-induced toxicity to immature testes via the PGAM5–DRP1 interaction(2024/02/15)
作者：Xiazhu Zhou, Yifan Hong, Jing Chen
期刊：ENVIRONMENTAL POLLUTION
DOI：10.1016/j.envpol.2024.123585
影響因子 ：8.900
引用產(chǎn)品：CL-0593
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Roles of ferroptosis in type 1 diabetes induced spermatogenic dysfunction(2024/02/17)
作者：Yalei Cao, Zirun Jin, Yu Xi
期刊：FREE RADICAL BIOLOGY AND MEDICINE
DOI：10.1016/j.freeradbiomed.2024.02.006
影響因子 ：7.400
引用產(chǎn)品：CL-0593
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The rare-earth yttrium induces cell apoptosis and autophagy in the male reproductive system through ROS-Ca2+-CamkII/Ampk axis(2023/07/20)
作者：Fangpeng Hou, Junyun Huang, Furong Qing
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115262
影響因子 ：6.800
引用產(chǎn)品：CL-0234 CL-0456 CL-0593 CL-0600 PM150210 PM150312
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X-box binding protein 1 caused an imbalance in pyroptosis and mitophagy in immature rats with di-(2-ethylhexyl) phthalate-induced testis toxicity(2023/03/27)
作者：Yifan Hong, Xiazhu Zhou, Qi Li
期刊：Genes & Diseases
DOI：10.1016/j.gendis.2023.02.030
影響因子 ：6.800
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N-acetylcysteine rescues meiotic arrest during spermatogenesis in mice exposed to BDE-209(2023/02/18)
作者：Yu Wei, Wenfeng Geng, Taifa Zhang
期刊：ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
DOI：10.1007/s11356-023-25874-0
影響因子 ：5.800
引用產(chǎn)品：CL-0593
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Dapagliflozin ameliorates diabetes-induced spermatogenic dysfunction by modulating the adenosine metabolism along the gut microbiota-testis axis(2024/01/05)
作者：Zirun Jin, Yalei Cao, Qi Wen
期刊：Scientific Reports
DOI：10.1038/s41598-024-51224-2
影響因子 ：4.600
引用產(chǎn)品：CL-0593
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BDE-209 induce spermatocytes arrest at early-pachytene stage during meiotic prophase I in mice(2021/12/20)
作者：Jinxia Zhai, Wenfeng Geng, Taifa Zhang
期刊：Toxicology
影響因子 ：4.500
引用產(chǎn)品：CL-0593
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Curcumin attenuates diphenyl phosphate-induced apoptosis in GC-2spd(ts) cells through activated autophagy via the Nrf2/P53 pathway(2023/12/14)
作者：Lai Wei, Siwen Li, Yu Ma
期刊：ENVIRONMENTAL TOXICOLOGY
影響因子 ：4.500
引用產(chǎn)品：CL-0593
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The crosstalk between M1 macrophage polarization and energy metabolism disorder contributes to polystyrene nanoplastics-triggered testicular inflammation(2023/08/26)
作者：Siwen Li, Lemei Liu, Gang Luo, Yu Yuan, Die Hu, Fang Xiao
期刊：FOOD AND CHEMICAL TOXICOLOGY
影響因子 ：4.300
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Epigallocatechin gallate alleviates mono-2-ethylhexyl phthalate-induced male germ cell pyroptosis by inhibiting the ROS/mTOR/NLRP3 pathway(2023/06/05)
作者：Yifan Hong, Xiazhu Zhou, Qi Li
期刊：TOXICOLOGY IN VITRO
影響因子 ：3.200
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